Multiprotein Printing by Light-Induced Molecular Adsorption

Advanced Materials (2016)

Pierre-Olivier Strale , Ammar Azioune , Ghislain Bugnicourt , Yohan Lecomte , Makhlad Chahid , Vincent Studer

Light-induced molecular adsorption of proteins (LIMAP) allows for quantitative sub-micrometer-resolution printing of multiple biomolecules. Surface-bound gradients are patterned within minutes over an entire glass cover-slip. LIMAP is used to perform selective immuno-assays, to dynamically control the adhesion of individual cells, and to achieve hierarchical co-cultures instrumental for tissue engineering.