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Dynamic Organization and Function of Synapses

Team Leader : Daniel Choquet

"Progress in science depends on new techniques, new discoveries and new ideas, probably in that order." Sydney Brenner

Daniel Choquet is a research director at the CNRS. He obtained an engineering degree from Ecole Centrale (Paris, France) in 1984 and completed his PhD in the lab of Henri Korn at the Pasteur Institute (Paris), studying ion channels in lymphocytes. He did a post-doctoral/sabbatical at Duke University (North Carolina, USA) in the laboratory of Michael Sheetz where he studied the regulation of integrin-cytoskeletal linkage by force. He setup his group in Bordeaux (France) at the Institute for Neuroscience and launched an interdisciplinary program on the combination of physiology, cell and chemical biology and high resolution imaging to study the functional role of the dynamic organization and trafficking of neurotransmitter receptors in synaptic transmission. He is now heading the Institute for Interdisciplinary Neuroscience and the Bordeaux Imaging Center core facility. He is also the director of the center of excellence BRAIN. He is a Member of the French Science Academy and has been awarded three consecutive ERC advanced grants. BioSketch (PDF).

You can check here the Personal page of Daniel Choquet.

General objective

The team develops several research topics, combining neuroscience, physics and chemistry in order to unravel the dynamics and nanoscale organization of multimolecular receptor complexes and their functional rôle in glutamatergic synaptic transmission in health and disease. Recently, the team has engaged in a major program to analyze and understand the interplay between AMPA type glutamate receptor nanoscale dynamics, synaptic plasticity and memory formation in the healthy and diseased brain. Our latest developments are a major thrust in combining molecular and physiological studies as well as analyzing neurodevelopmental disorders related to synapse dysfunction.

Project leaders (Click to reach subprojects)

Anna Brachet Daniel Choquet Françoise Coussen Eric Hosy Matthieu Sainlos

Research Projects

Team Project Summary


Cytoskeleton and membrane interplay in synaptic organization and transmission (Anna Brachet).


Chemical Biology and Protein Engineering (Matthieu Sainlos)


Impact of auxiliary proteins on AMPAR transport, trafficking and physiology (Françoise Coussen).


nanoscale excitatory synaptic physiology (Eric Hosy).


Contribution of AMPAR surface trafficking to Short and long term synaptic plasticity (Daniel Choquet)


Synapse dysfunction in neurodevelopmental disorders (Eric Hosy, Daniel Choquet)





  • Super Resolution Microscopy
  • Slice physiology
  • Chemical biology, Protein Engineering
  • Biochemistry
  • News

    Co-organization and coactivation of AMPAR, NMDAR, and mGluR

    Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses.

    The nanoscale co-organization of neurotransmitter receptors facing presynaptic release sites is a fundamental determinant of their coactivation and of synaptic physiology. At excitatory synapses, how endogenous AMPARs, NMDARs, and mGluRs are co-organized inside the synapse and their respective activation during glutamate release are still unclear. Combining single-molecule super resolution microscopy, electrophysiology, and modeling, we determined the average quantity of each glutamate receptor type, their nanoscale organization, and their respective activation. We observed that NMDARs form a unique cluster mainly at the center of the PSD, while AMPARs segregate in clusters surrounding the NMDARs.mGluR5 presents a different organization and is homogenously dispersed at the synaptic surface. From these results, we build a model predicting the synaptic transmission properties of a unitary synapse, allowing better understanding of synaptic physiology.

    Authors: Julia Goncalves, Tomas M. Bartol, Côme Camus, Florian Levet, Ana Paula Menegolla,Terrence J. Sejnowski, Jean-Baptiste Sibarita, Michel Vivaudou, Daniel Choquet and Eric Hosy

    - Publication in PNAS, June 8, 2020
    - Contact: Eric Hosy

    + Cf Bordeaux Neurocampus website here

    AMPA receptor nanoscale dynamic organization and synaptic plasticities

    Review on “AMPA receptor nanoscale dynamic organization and synaptic plasticities” in Current Opinion in Neurobiology 2020

    The emergence of new imaging techniques and molecular tools has refreshed our understanding of the principles of synaptic transmission and plasticity. Superresolution imaging and biosensors for measuring enzymatic activities in live neurons or neurotransmitter levels in the synaptic cleft are giving us an unprecedented integrated and nanoscale view on synaptic function. Excitatory synapses are now conceptualized as organized in subdomains, enriched with specific scaffolding proteins and glutamate receptors, molecularly organized with respect to the pre-synaptic source of glutamate.

    This new vision of basic synaptic transmission changes our understanding of the molecular modifications which sustain synaptic plasticities. Long-term potentiation can no longer be explained simply by an increase in receptor content at the synapse. We review here the latest data on the role of nanoscale and dynamic organization of AMPA type glutamate receptors on synaptic transmission at both basal state and during short and long-term plasticities.

    - Current Opinion in Neurobiology - Volume 63, August 2020, Pages 137-145
    - Contacts: Daniel Choquet and Eric Hosy

    A discrete presynaptic vesicle cycle for neuromodulator receptors - Neuron, December 2019

    A major function of GPCRs is to inhibit presynaptic neurotransmitter release, requiring ligand-activated receptors to couple locally to effectors at terminals. The current understanding of how this is achieved is through receptor immobilization on the terminal surface. Here, we show that opioid peptide receptors, GPCRs that mediate highly sensitive presynaptic inhibition, are instead dynamic in axons. Opioid receptors diffuse rapidly throughout the axon surface and internalize after ligand-induced activation specifically at presynaptic terminals. We delineate a parallel regulated endocytic cycle for GPCRs operating at the presynapse, separately from the synaptic vesicle cycle, which clears activated receptors from the surface of terminals and locally reinserts them to maintain the diffusible surface pool. We propose an alternate strategy for achieving local control of presynaptic effectors that, opposite to using receptor immobilization and enforced proximity, is based on lateral mobility of receptors and leverages the inherent allostery of GPCR-effector coupling.

    Damien Jullié, Miriam Stoeber, Jean-Baptiste Sibarita, Hanna L. Zieger, Thomas M. Bartol, Seksiri Arttamangkul, Terrence J. Sejnowski, Eric Hosy, and Mark von Zastrow

    - Neuron. 2019 Dec 5 - doi: 10.1016/j.neuron.2019.11.016.
    - Contact: Eric Hosy

    Multicolor Spectrin labeling (ML Jobin)

    This is a rat hippocampal neuron in culture stained with a series of markers



    Nature Neuroscience Review - Choquet D., Sainlos M. and Sibarita J.B.

    We review the latest developments for labelling and functionalizing proteins with small localization and functionalized reporters. We present how these molecular tools are combined with the development of a wide variety of imaging methods that break either the diffraction barrier or the tissue penetration depth limits. We put these developments in perspective to emphasize how they will enable step changes in our understanding of the brain.


    BRAIN_2030 «Grand Programme de Recherche» de l'université de Bordeaux

    The BRAIN_2030 project (“Bordeaux Region Aquitaine Initiative for the future of Neurosciences”), submitted by Bordeaux Neurocampus within the “GPR - Major Research Program” of the University of Bordeaux, and headed by Daniel Choquet, has just been approved. It is one of the 7 projects selected out of the 15 submitted in June 2020.

    A dialogue phase is planned to validate the final budget that will be allocated for the period 2021-2025. Additional funding for an additional period will be granted after an interim evaluation in 2025.

    The project starts in September 2021.

    + Find more details on the Université of Bordeaux (UB) and the Bordeaux Neurocampus (BN) websites.

    Access the hidden side of neuronal proteins through the expansion of the genetic code

    Progress in biological imaging is intrinsically linked to advances in labeling methods. The explosion in the development of high-resolution and super-resolution imaging calls for new approaches to label targets with small probes. These should allow to faithfully report the localization of the target within the imaging resolution – typically nowadays a few nanometers - and allow access to any epitope of the target, in the native cellular and tissue environment. We report here the development of a complete labeling and imaging pipeline using genetic code expansion and non-canonical amino acids in neurons that allows to fluorescently label masked epitopes in target transmembrane proteins in live neurons, both in dissociated culture and organotypic brain slices. This allows us to image the differential localization of two AMPA receptor (AMPAR) auxiliary subunits of the transmembrane AMPAR regulatory protein family in complex with their partner with a variety of methods including widefield, confocal, and dSTORM super-resolution microscopy.

    Authors: Diogo Bessa-Neto & Gerti Beliu, Alexander Kuhlemann, Valeria Pecoraro, Sören Doose, Natacha Retailleau, Nicolas Chevrier, David Perrais, Markus Sauer & Daniel Choquet

    Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids unveils masked epitopes in live neurons.
    Nature Communications (November 2021) DOI: 10.1038/s41467-021-27025-w

    Contact: Daniel Choquet

    + Cf. INSB website (French) here
    + Cf. the press release on the University of Würzburg website here

    Daniel Choquet: prix 2022 de l’Academie nationale des sciences, belles lettres et arts de Bordeaux

    Academie nationale des sciences, belles lettres et arts de Bordeaux aims to help develop the ideas, work and research of Academicians. Each year, it rewards in particular personalities for their work or their research or for all of their work in the field of science, literature or the arts.

    Thus, in 2022, it was Daniel Choquet, CNRS research director, who was awarded "le grand prix 2022 de l’Academie nationale des sciences, belles lettres et arts de Bordeaux"! Indeed, he achieved this distinction thanks to his main scientific achievement: the discovery that neurotransmitter receptors are in constant motion in the neuronal membrane and that the regulation of this traffic profoundly regulates synaptic transmission. Daniel Choquet will receive his award on March 28 from Pierre Hurmic, Mayor of Bordeaux.

    Learn more about: Le grand prix 2022 de l’Academie nationale des sciences, belles lettres et arts de Bordeaux

    They talk about it too (articles in French): INSB and Bordeaux Neurocampus

    Do you want to know more? Nolwenn Cloarec, communication officer:

    Regulation of different phases of AMPA receptor intracellular transport by 4.1N and SAP97, eLife

    Caroline Bonnet1, Justine Charpentier1, Natacha Retailleau1, Daniel Choquet1,2, Françoise Coussen1*
    1University of Bordeaux, CNRS, Interdisciplinary Institute for Neuroscience, Bordeaux, France; 2Bordeaux Imaging Center, Bordeaux, France

    eLife. 2023-04-20


    Françoise Coussen, Director of research at the CNRS at IINS worked on AMPAR intracellular transport and directed this work helped by Daniel Choquet. Caroline Bonnet, PhD student, performed the experiments helped by Justine Charpentier who performed all biochemistry experiments and by Natacha Retailleau (molecular biology).

    Find the explanations of the scientists of this publication

    Identification of the molecular mechanisms regulating the intracellular transport of glutamate receptors: a new pathway for controlling synaptic plasticity

    "The modulation of the efficiency of synaptic transmission between neurons is one of the fundamental processes of memory and learning phenomena. This regulation of the strength of synaptic transmission is largely driven by changes in the number of receptors present at the synapse. In this work, the researchers identify a new mechanism for controlling the establishment of receptors at the level of the synapse through the control of their intracellular transport.

    Neurotransmitter receptors, and in particular glutamate receptors, are concentrated in synapses in front of neurotransmitter release sites. However, in the process of their biogenesis, these receptors are synthesized at the level of the endoplasmic reticulum, most of the time several hundred microns from the synapses. They must therefore be transported to the synapses. Our previous work had made possible to visualize for the first time the intracellular transport of AMPA-type glutamate receptors, responsible for the majority of the rapid excitatory transmission between neurons. These receptors are transported rapidly (1-2 microns per second) in vesicles circulating on the microtubules using molecular motors. We observed that, surprisingly, this transport was strongly regulated by neuronal activity.

    In this new work, we have identified the molecular mechanisms responsible for these regulations. The cytosolic C-terminal domain of the AMPAR GluA1 subunit is specifically associated with two proteins, 4.1 N and SAP97. We analyzed how interactions between GluA1 and 4.1N or SAP97 regulate GluA1 transport and its exocytosis under basal conditions and after induction of synaptic plasticity (LTP). Our results identify differential roles of 4.1N and SAP97 in controlling the different phases of transport and membrane integration of GluA1.

    This work opens new perspectives in understanding the molecular mechanisms that control the establishment and maintenance of glutamate receptors at the synapse during synaptic plasticity."

    Daniel Choquet is a member of the 2023 Fulbright France

    Created in 1946 at the proposal of the eponymous US senator, Fulbright is an international academic mobility program of the US government. The aim of the program is to promote educational and cultural exchanges between France and the United States.

    Since its launch, 21,244 students from both countries have benefited from the program:

    • 12,294 French students have gone to the United States of America,
    • 8,950 Americans have come to France.

    Daniel Choquet (director of research at the CNRS, director of IINS, the BIC, the cluster of excellence BRAIN_2030 and team leader at IINS) has just been selected as a laureate of the Fulbright France program. He will be spending a 7 month sabbatical stay in Denver in 2024.

    Why did you apply to the Fulbright France Program?

    “I was getting organized to perform a 7 month sabbatical in Denver in 2022, in the lab of Pr. Mark Dell’Acqua. Given the cost of living in the US, I needed additional funding to support my stay. The Fulbright organization is a very prestigious academic mobility program of the US government and it was thus natural for me to apply, particularly given that there is a specific partnership with our region Nouvelle-Aquitaine.”

    What does it mean to you?

    “Well, it does mean a lot. First, in searching the Fulbright alumni file, I found out that both my parents were fulbrighters in the 50s while they did post-docs in Princeton, my mother with Albert Einstein. Second, I realized when I obtained this fellowship that when you enter a new family, the family of Fulbrighters, beyond the money, you enter a support network all over the US that will be both very interesting and valuable.”

    Will you take this opportunity to discover or develop a research topic?

    “Absolutely, the Department of Pharmacology at the University of Colorado in Denver that I’ll join hosts a large number of high profile neurobiologists that develop orginal cell biology approaches.

    We will join our forces with Mark Dell’Acqua and Matthew Kennedy to develop new methods and approaches to control receptor trafficking and visualization.”

    What do you think this program will bring you, both professionally and personally?

    “In addition to the funding that will help me live there, being a Fulbright fellow in the US is really recognized and will help me develop my network and meet many academics in various disciplines. Fulbright fellow also have a mission to be ambassadors of their country, and I certainly intend to introduce to colleagues to some French cuisine specialties!”

    #IMadteIt: Marie-Lise Jobin, a post-doctoral researcher starting out as an associate professor

    Marie-Lise Jobin is currently a post-doctoral researcher in Daniel Choquet’s "Dynamic organization and function of synapses" team. Interested in the role of the cytoskeleton in the function and structure of dendritic spines, the scientist is supervised by Anna Brachet. Marie-Lise recently obtained a permanent teaching-research position at the Institut National Polytechnique de Bordeaux (Bordeaux INP). Here, she looks back on her career.

    What is your background?
    "I studied biology and structural biochemistry at the University of Bordeaux. During my Master’s and PhD, I worked in many different laboratories. First, I spent three months working at the University of Guelph in Ontario, Canada. Then, for my PhD, I joined the Institute of Chemistry and Biology of Membranes and Nano-objects (CBMN) in Pessac. On completion of my studies, I spent a year as a post-doctoral fellow at the Nutrition and Integrative Neurobiology Laboratory (Nutrineuro) in Bordeaux. I then spent over three years at the University of Würzburg in Bavaria, Germany. And for the last four years I’ve been at IINS. My post-doctoral adventure will finally come to an end at the end in September 2023, and I’ll be taking up a position as an associate professor in September!"

    Why did you join IINS?
    "Generally speaking, I’ve always been interested in biomolecular interactions involving cell membranes. I first worked on synthetic membrane models. However, I’ve always wanted to study more physiological systems. So the neuroscience field allows me to work with systems closer to physiology, and to use my highly interdisciplinary skills. [...] Anna Brachet’s field of research on the role of cytoskeletal proteins, in particular spectrins, and their partners, in the regulation, function and mechano-transduction of dendritic spines fit perfectly my research interests. Moreover, IINS is considered one of the most recognized institutes in the field of neuroscience. Above all, IINS is part of a synergistic system, with close relations to the Bordeaux Imaging Center (BIC). It was a unique opportunity to develop my skills in cutting-edge microscopy techniques and gain access to considerable knowledge in this field!"

    Can you tell us about your research?
    "I’m trying to understand the role of cytoskeletal proteins, beta spectrins, in neurons, and more specifically in dendritic spines, which are the seat of neuronal transmission. My results showed that beta spectrins are co-organised on a nanoscopic scale in dendritic spines and are particularly important for the stability of these structures. Their membrane or cytoskeleton partners are all the more important in maintaining and stabilising these spectrins under the membrane and influence their nano-organisation."

    As a woman in science, what difficulties have you encountered?
    "My biggest difficulty has always been a lack of self-confidence. But throughout my career I’ve been lucky enough to meet scientists, men and women who have had faith in me, and who have always supported and encouraged me along the way."

    Why do women need to be more recognised in the scientific community?
    "It seems quite logical to me that gender diversity, or diversity of any kind, leads to better, more creative and innovative science. I can see that things are changing, slowly but surely, in the right direction, and I’m optimistic for the future!"

    Any advice for young researcher?
    "I’m proud to have got where I am, to have succeeded in obtaining a permanent position in academia, and to have stayed the course despite many years of not knowing what would happen and never giving up. You have to persevere. It’s often the fear of failing that stops us from moving forward, so don’t hesitate, dare to take the plunge and, above all, trust yourself."

    2 days of exciting science on synapse biology around the PhD defense of Agata Nowacka

    Monday 6th November 2023

    Workshop: Virtual Presynaptic Terminal

    We invite you to a workshop where a collaborative team from University College London (UCL) and the University of Warwick will introduce a computational modelling framework that enables in silico exploration of the mechanisms of Ca²⁺-driven neurotransmitter release in different synapses.

    Morning session 9:00 – 12:30

    • Kirill Volynski: Introduction to the modelling framework with examples linking the model and experimental data.

    • Yulia Timofeeva: 3D modelling of presynaptic Ca2+ dynamics, covering Ca2+ influx, buffering, and diffusion.

    • Chris Norman: Modelling Ca 2+ activation of vesicular release and short-term synaptic plasticity.

    • Round table: model expansion across the synaptic cleft.

    Afternoon session 14:00 – 17:00

    • Yulia Timofeeva and Chris Norman: hands-on training for application of the virtual presynaptic terminal model. Contact the presenters to book a one-to-one training session.

    Registration before October 20:

    Tuesday 7th November 2023

    Seminar Molecular and cellular mechanisms of synapse physiology

    Venue: Centre Broca Nouvelle-Aquitaine (Amphitheater Broca)


    9h30 - Maria Passafaro "Unraveling PCDH19-related pathogenic mechanisms in Developmental and Epileptic Encephalopathy 9 (DEE9)"

    10h10 - Andrea Barberis 'Spatial determinants for the interactions of glutamatergic and GABAergic synapses in dendrites of hippocampal pyramidal neurons"

    10h50 - Kirill Volynski "Synergistic regulation of neurotransmitter release by different synaptotagmin isoforms"

    11h30 - Aude Panatier "Astrocytic EphB receptors control NMDAR functions and memory"

    14h - PhD defense of Agata Nowacka "Differential contributions of pre- and postsynaptic components in tuning high-frequency short-term synaptic plasticity"


    Kirill Volynski (, UCL Queen Square Institute of Neurology

    Chris Norman (, UCL Queen Square Institute of Neurology

    Yulia Timofeeva (, Department of Computer Science, University of Warwick

    Selected Publications

  • Angela M Getz, Mathieu Ducros, Christelle Breillat, Aurélie Lampin-Saint-Amaux, Sophie Daburon, Urielle François, Agata Nowacka, Mónica Fernández-Monreal, Eric Hosy, Frédéric Lanore, Hanna L Zieger, Matthieu Sainlos, Yann Humeau, Daniel Choquet
  • High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning Science Advances (2022)
    Display the article MORE

  • Choquet D., Sainlos M. and Sibarita J.B.
  • Advanced imaging and labelling methods to decipher brain cell organization and function Nature reviews Neuroscience (2021)
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  • Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang and Yasunori Hayashi 
  • CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation Nature Neuroscience (2021)
    Display the article MORE

  • Diogo Bessa-Neto, Gerti Beliu, Alexander Kuhlemann, Valeria Pecoraro, Sören Doose, Natacha Retailleau, Nicolas Chevrier, David Perrais, Markus Sauer & Daniel Choquet
  • Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids unveils masked epitopes in live neurons Nature Communications (2021)
    Display the article MORE

  • Laurent Groc & Daniel Choquet
  • Linking glutamate receptor movements and synapse function Science (2020)
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  • Julia Goncalves, Tomas M Bartol, Côme Camus, Florian Levet, Ana Paula Menegolla, Terrence J Sejnowski, Jean-Baptiste Sibarita, Michel Vivaudou, Daniel Choquet, Eric Hosy
  • Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses Proc Natl Acad Sci U S A (2020)

  • Tiago Campelo, Elisabete Augusto, Nicolas Chenouard, Aron de Miranda, Vladimir Kouskoff, Come Camus, Daniel Choquet, Frédéric Gambino
  • AMPAR-Dependent Synaptic Plasticity Initiates Cortical Remapping and Adaptive Behaviors during Sensory Experience Cell Report (2020)
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  • Florelle Domart, Peter Cloetens, Stéphane Roudeau, Asuncion Carmona, Emeline Verdier, Daniel Choquet, Richard Ortega
  • Correlating STED and synchrotron XRF nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendrites eLife (2020)
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  • Humeau, Y. and Choquet, D.
  • The next generation of approaches to investigate the link between synaptic plasticity and learning. Nature Neuroscience (2019)
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  • Charlotte Rimbault, Kashyap Maruthi, Christelle Breillat, Camille Genuer, Sara Crespillo, Virginia Puente-Muñoz, Ingrid Chamma, Isabel Gauthereau, Ségolène Antoine, Coraline Thibaut, Fabienne Wong Jun Tai, Benjamin Dartigues, Dolors Grillo-Bosch, Stéphane Claverol, Christel Poujol, Daniel Choquet, Cameron D Mackereth, Matthieu Sainlos
  • Engineering selective competitors for the discrimination of highly conserved protein-protein interaction modules Nature Communication (2019)
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  • Emilie Hangen, Fabrice P Cordelières, Jennifer D Petersen, Daniel Choquet, Françoise Coussen
  • Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR Cell Report (2018)
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  • Penn, A.C., Zhang, C.L., Georges, F., Royer, L., Breillat, C., Hosy, E., Petersen, J.D., Humeau, Y., and Choquet, D.
  • Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors Nature (2017)
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  • Audrey Constals, Andrew C Penn, Benjamin Compans, Estelle Toulmé, Amandine Phillipat, Sébastien Marais, Natacha Retailleau, Anne-Sophie Hafner, Françoise Coussen, Eric Hosy, Daniel Choquet
  • Glutamate-induced AMPA receptor desensitization increases their mobility and modulates short-term plasticity through unbinding from Stargazin Neuron (2015)
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  • Anne-Sophie Hafner, Andrew C Penn, Dolors Grillo-Bosch, Natacha Retailleau, Christel Poujol, Amandine Philippat, Françoise Coussen, Matthieu Sainlos, Patricio Opazo, Daniel Choquet
  • Lengthening of the Stargazin Cytoplasmic Tail Increases Synaptic Transmission by Promoting Interaction to Deeper Domains of PSD-95 Neuron (2015)
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  • Deepak Nair, Eric Hosy, Jennifer D Petersen, Audrey Constals, Gregory Giannone, Daniel Choquet, Jean-Baptiste Sibarita
  • Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95 Journal of Neuroscience (2013)
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  • Heine, M., Groc, L., Frischknecht, R., Beique, J.C., Lounis, B., Rumbaugh, G., Huganir, R.L., Cognet, L., and Choquet, D.
  • Surface mobility of postsynaptic AMPARs tunes synaptic transmission Science (2008)
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  • Aren J Borgdorff and Daniel Choquet
  • Regulation of AMPA receptor lateral movements Nature (2002)
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    « Researcher »

    BRACHET Anna Researcher +33533514732
    CHOQUET Daniel Researcher +33533514715
    COUSSEN Francoise Researcher +33533514734
    HOSY Eric Researcher +33533514730
    SAINLOS Matthieu Researcher +33533514731

    « Technical Staff »

    BELZANNE Pauline Technical staff +33533514700
    BREILLAT Christelle Technical staff +33533514731
    CHARPENTIER Justine Technical staff +33533514776
    CHEVRIER Nicolas Technical staff +33533514733
    Daburon Sophie Technical staff +33533514732
    LEMOIGNE Cécile Technical staff +33533514732
    VERRON LOris Technical staff +33533514700

    « Postdoc »

    DOMART Florelle Postdoc +33533514700
    GETZ Angela Postdoc +33533514735
    IGNACZ Attila Postdoc +33533514700
    NOWACKA Agata Postdoc +33533514749
    STAJANO Daniele Postdoc +33533514700

    « PhD student »

    CHANDRA Meera PhD student +33533514700
    CUENOT Chloé PhD student +33533514700
    DARRIBERE Manon PhD student +33533514700
    LEVAL Léa PhD student +33533514700
    SARZYNSKI Léa PhD student +33533514700
    TRIVUNOVIC Ivana PhD student +33533514749
    VILLICANA-MUÑOZ Viviana PhD student +33533514700

    « Alumni & Guests »

    Former group members, follow-up last known position

    • Aren borgdorff - 1997-2000, Industry
    • Arnauld Sergé - 1997-2001, Assistant professor Marseille
    • Marianne Renner - 2004-2006, Professor, Paris
    • Caroline Dequidt - 2004-2007, Industry
    • Cécile Bats - 2004-2007, Post-doc, London
    • Martin Heine - 2003-2007, Junior group leader, Magdeburg
    • Enrica Petrini - 2005-2008, Post-doc, Genoa
    • Cezar Tigaret - 2006-2009, Lecturer, Bristol
    • Helge Ewers - 2007-2009, Group leader, Berlin
    • Arnaud Frouin - 2007-2010, Labmanager, NYC
    • Leandro Royer - 2009-2012, Post-doc, Boston
    • Patricio Opazo - 2008-2013, Group leader, Brisbane
    • Jary Delgado - 2009-2013, Post-doc, Chicago
    • Deepak Nair - 2009-2013, Group leader, Bengalor
    • Damien Jullié - 2009-2013, Post-doc, San Francisco
    • Audrey Constal - 2010-2013, Teacher
    • Axel Athane - 2011-2013, Industry
    • Dolors Grillo, 2011-2013, Post-doc, Spain
    • Anne-Sophie Hafner - 2010-2014, Post-doc, Frankfurt
    • Isabelle Gautherau - 2012-2014, Industry
    • Amandine Philippat - 2013-2015, Industry
    • Andrew Penn - 2010-2015, Junior group leader, Sussex
    • Hongyu Zhang - 2010-2015, Post-doc, University of Bergen
    • Estelle Toulme - 2013-2015, Post-doc, Berlin
    • Jennifer Petersen - 2009-2016, Post-doc, NIH
    • Yulia Krapivkina - 2013-2016, Industry
    • Ngoc Van Thi Nhu - 2013-2016, Engineer, Montpellier
    • Emilie Hangen - 2014-2017
    • Ségolène Antoine - 2015-2017, French Industry
    • Sara Crespillo - 2015-2017, Post-doc, Cambridge
    • Célia Michel - 2014-2017, French Industry
    • Benjamin Compans - 2014-2018, Post-doc, London
    • Lucile Pret - 2018, Engineer, London
    • Julia Goncalves – 2015 – 2018, Engineer, Bordeaux Neurocampus
    • Murielle Fevre - 2017-2018
    • Camille Genuer - 2017-2018, Engineer, French Industry
    • Carla Montecinos - 2013-2018, post-doc Bordeaux
    • Charlotte Rimbault – 2014-2019, Post-doc, Copenhagen
    • Magalie Martineau – 2015-2019, Post-doc, Paris
    • Léa Claverie – 2015 - 2019, UK
    • Florelle Domart - 2016-2019, Post-doc Goettingen
    • David Perrais - 2011-2020, Group Leader
    • Sylvia Sposini - 2018-2020, Post-doc, Bordeaux
    • Lou Bouit - 2018-2020, Engineer, Bordeaux 
    • Côme Camus - 2018-2021, Medical Intern, Bordeaux 
    • Caroline Bonnet - 2017-2021
    • Inès Gonzalès-Calvo - 2019-2021
    • Valeria Pecoraro - 2019-2021


    • Raffaella Adami, Pisa - January, June 2001
    • Andres Villu Maricq, Utah - November 2003
    • Radhika Reddy, Worley lab - June 2003
    • Michael Ehlers, Duke University - March, September 2006
    • Renatto Frischknecht, Gundelfinger lab - April 2006, September 2006
    • Laura Andreae, Fine lab - April 2006, November 2006
    • Anna Carbone, Plested Lab - January, April 2012
    • Beulah Leitch, Otago University - October 2013
    • Andrew Plested, FMP Berlin - October 2015, February 2016
    • Nikolaj Riis Christensen, Copenhagen University - June-December 2017
    • Anne Brunet, Stanford University - April-July 2019
    • Pin Wu Liu, Kyoto University Graduate School of Medicine - January 2020
    • Boram Lee, Johannes W. Hell UCDavis - January-June 2020